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A 46-year-old man ingested 1,500 mg of potassium cyanide in a suicide attempt.He survived,but later developed a severe parkinsonian syndrome.MRI revealed multiple areas of low-signal intensity in the globus pallidus and posterior putamen.A 6-fluorodopa PET study revealed bilateral decreased uptake in the basal ganglia.The evidence of functional impairment of dopaminergic nigrostriatal neurons is related either to direct toxicity of cyanide or to the effects of cerebral hypoxia secondary to cyanide intoxication. |
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CAT scan,emission CAT scan,emission,abnormal cyanide poison lenticular nucleus,lesion of lenticular nucleus,lesion of,bilateral MRI MRI,abnormal Parkinson disease Parkinson disease,drug induced Parkinsonism syndrome
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