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A 46-year-old man ingested 1,500 mg of potassium cyanide in a suicide attempt.He survived,but later developed a severe parkinsonian syndrome.MRI revealed multiple areas of low-signal intensity in the globus pallidus and posterior putamen.A 6-fluorodopa PET study revealed bilateral decreased uptake in the basal ganglia.The evidence of functional impairment of dopaminergic nigrostriatal neurons is related either to direct toxicity of cyanide or to the effects of cerebral hypoxia secondary to cyanide intoxication. |
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CAT scan,emission
CAT scan,emission,abnormal
cyanide poison
lenticular nucleus,lesion of
lenticular nucleus,lesion of,bilateral
MRI
MRI,abnormal
Parkinson disease
Parkinson disease,drug induced
Parkinsonism syndrome
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