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The efficacy and safety of oral cyclosporin 10 mg/kg per day in Behcet's disease were compared in a randomised double-masked study with those of colchicine,1 mg orally per day,and were also investigated in a long-term open study.The double-masked study showed that cyclosporin was effective in treating not only the ocular manifestations of Behcet's disease but also oral aphthous ulcer,dermal lesions,and genital ulceration.Efficacy did not weaken during long-term treatment. |
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