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Continuous Levodopa Infusions to Treat Complex Dystonia in Parkinson's Disease
Neurol 39:888-891, Sage,J.I.,et al, 1989
See this aricle in Pubmed
Article Abstract
We report the clinical spectrum of 3 patients with Parkinson's disease who experienced complex patterns of levodopa-related dystonia.Dystonia was unrelieved by multiple medication regimens but responded well to continuous,duodenal levodopa infusions.Patients were able to remain mobile without severe dystonia despite a very narrow window of benefit between the levodopa concentration necessary to achieve the"on"state and that which caused the onset of dystonic spasms.
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dystonia
dystonia,treatment of
infusion pump
L-dopa
L-dopa,drug interactions with and side effects of
L-dopa,enteral infusion,continuous
Parkinson disease
Parkinson disease,treatment of
treatment of neurologic disorder
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