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Gabapentin in Orthostatic Tremor:Results of a Double-Blind Crossover with Placebo in four Patients
Neurol 51:880-882, Onofrj,M.,et al, 1998
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Article Abstract
We treated four patients affected by orthostatic tremor(OT)with gabapentin in increasing doses(300 to 2,400 mg/d).OT was evaluated with patients self-monitoring scales,tremor rating scales,electromyography(EMG)showing the 14-to 18 Hz frequencies,and EMG frequency analysis.All patients had transitory responses to clonazepam.Gabapentin induced disappearance of OT in three patients and consistent reduction in one.Crossover to placebo induced reappearance of tremor.
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