Tenecteplase for Acute Non-Large Vessel Occlusion 4.5 to 24 Hours After IschemicStroke, The OPTION Randomized Clinical Trial
JAMA doi:10.1001/JAMA.2026.0210, Ma,G.,et al, 2026
A Randomized Trial of Tenecteplase in Acute Central Retinal Artery Occlusion
NEJM 394:442-450, Ryan,S.J.,et al, 2026
Direct to Angiography Suite Without Stopping for Computed Tomography Imaging for Patients with Acute Stroke
JAMA Neurol 78:1099-1107, Requena, M.,et al, 2021
Drip and Ship Versus Direct to Comprehensive Stroke Center
Stroke 48:233-238, Holodinsky, J.K.,et al, 2016
Treatment Concepts for Wake-Up Stroke and Stroke with Unknown Time of Symptom Onset
Stroke 46:2707-2713, Thomalla, G. & Gerloff, C., 2015
4.5-Hour Time Window for Intravenous Thrombolysis with Recombinant Tissue-Type Plasminogen Activator is Established Firmly
Stroke 45:912-913,916, Schellinger, P.D. & Kohrmann, M., 2014
The 4.5-HourTime Window for Intravenous Thrombolysis with Intravenous Tissue-Type Plasminogen Activator is Not Firmly Established
Stroke 45:915-915,916, Wechsler, L.R., 2014
Endovascular Treatment for Acute Ischemic Stroke-Still Unproven
NEJM 368:952-955, Chimowitz,M., 2013
A Trial of Imaging Selection and Endovascular Treatment for Ischemic Stroke
NEJM 368:914-923,952, Kidwell, C.S.,et al, 2013
Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke
NEJM 368:893-903,952, Broderick, J.P.,et al, 2013
Treatment of Patients with Suspected Ischemic Stroke of Undetermined Onset and Negative Head Computed Tomography Scan
Stroke 44:1494-1495, Adams, H., 2013
A Plain Computed Tomography Scan is Sufficient to Consider Thrombolysis in Patients with Unknown Time of Onset
Stroke 44:1492-1493, Alexandrov, A., 2013
Intraarterial Thrombolysis Within the First Three Hours After Acute Ischemic Stroke in Selected Patients
Stroke 40:2611-2612,2615, Moonis,M., 2009
Is Intraarterial tPA Within 3 Hours the Treatment of Choice for Selected Stroke Patients? No
Stroke 40:2613-2614,2615, Lindley,R.I., 2009
Perfusion-Weighted Imaging/Diffusion-Weighted Imaging Mismatch on MRI Can Now be Used to Select Patients for Recombinant Tissue Plasminogen Activator Beyond 3 Hours
Stroke 36:1099-1100, 1100, Zivin,J.A., 2005
Perfusion-Weighted Imaging/Diffusion-Weighted Imaging Mismatch on MRI Can Now Be Used to Select Patients for Recombinant Tissue Plasminogen Activator Beyond 3 Hours
Stroke 36:1098-1099,1100, Schellinger,P.D. &Fiebach,J.B., 2005
Are There Time-Dependent Differences in Diffusion and Perfusion Within the First 6 Hours After Stroke Onset?
Stroke 35:2099, Fiehler,J.,et al, 2004
Imaging-Based Decision Making in Thrombolytic Therapy for Ischemic Stroke
Stroke 34:575-583, Schellinger,P.D.,et al, 2003
To Use Perfusion Imaging or Not in Patient Selection for Late Window Endovascular Thrombectomy?
Neurol 100:1039-1040, Katsanos,A.H.,et al, 2023
Endovascular Treatment and Thrombolysis for Acute Ischemic Stroke in Patients with Premorbid Disability or Dementia
Stroke 53:e204-e217, Ganesh, A.,et al, 2022
Endovascular Therapy for Stroke Due to Basilar Artery Occlusion
Stroke 52:3410-3413, Nguyen, T.N. & Strbian, D., 2021
Treatment and Outcome of Hemorrhagic Transformation after Intravenous Alteplase in Acute Ischemic Stroke
Stroke 48:e343-e361, Yaghi, S.,et al, 2017
Carotid Near-Occlusion: A Comprehensive Review, Part 2- Prognosis and Treatment, Pathophysiology, Confusions, and Areas for Improvement
AJNR 37:200-204, Johansson, E. & Fox, A.J., 2016
Microbleed Status and 3-Month Outcome After Intravenous Thrombolysis in 717 Patients with Acute Ischemic Stroke
Stroke 46:2458-2463,2403, Turc, G.,et al, 2015
Intravenous Fibrinolytic Therapy in Central Retinal Artery Occlusion
JAMA Neurol 72:1148-1154, Schrag, M.,et al, 2015
Reperfusion Therapies for Wake-Up Stroke
Stroke 45:1869-1875, Buck, D.,et al, 2014
Thrombolysis for Ischemic Stroke Associated with Infective Endocarditis
Stroke 44:2917-2919, Asaithambi, G.,et al, 2013
The Types of Neurological Deficits Might Not Justify Withholding Treatment in Patients with Low Total National Institutes of Health Stroke Scale Scores
Stroke 43:782-786,625, Leira,E.C.,et al, 2012
Elderly Patients are at Higher Risk for Poor Outcomes after Intra-Arterial Therapy
Stroke 43:2356-2361, Chandra, R.V.,et al, 2012
Thrombosis of the Cerebral VEins and Sinuses
NEJM 352:1791-1798, Stam,J., 2005
Endovascular Therapy for Medium-Vessel Occlusion Stroke - Narrowing the Target Population
NEJM 394:1955-1957,1894, Ospel,J.M. & Hill, M.D., 2026
Idiopathic Normal-Pressure Hydrocephalus
NEJM 393:2243-2253, 2264, Johnson,M.D.,& Williams, M.A., 2025
Patent Foramen Ovale Management for Secondary Stroke Prevention:State-of-the-Art Appraisal of Current Evidence
Stroke 55:236-247, Sposato,L.A.,et al, 2024
Vascular Malformations of the Central Nervous System
www.UptoDate.Com, March, Singer,R.J.,et al, 2024
Tenecteplase Versus Standard of Care for Minor Ischaemic Stroke with Proven Occlusion (TEMPO-2): A Randomised, Open Label, Phase 3 Superiority Trial
Lancet 403:2597-2605, Coutts,S.B.,et al, 2024
Endovascular Therapy or Medical Management Alone for Isolated Posterior Cerebral Artery Occlusion: A Multicenter Study
Stroke 54:928-937, Sabben,C.,et al, 2023
Risk of Stroke, Death, and Myocardial Infarction Following Transcarotid Artery Revascularization vs Carotid Endarterectomy in Patients with Standard Surgical Risk
JAMA Neurol 80:437-444,435, Liang,P.,et al, 2023
Primary Diffuse Leptomeningeal Melanocytosis, A Diagnoatic Conundrum
Neurol 101:e576-3580, Selvarajan,J.M.P.,et al, 2023
In Stroke, When is a Good Outcome Good Enough?
NEJM 386:1359-1361, Schwamm, L.H., 2022
Endarterectomy, Stenting, or Medical Treatment for Symptomatic Carotid Near-Occlusion: Results from CAOS, a Multicenter Registry Study
AJNR 43:1304-1310, Garcia-Pastor, A.,et al, 2022
Thrombectomy versus Medical Management in Mild Strokes due to Large Vessel Occlusion: Exploratory Analysis from the EXTEND-IA Trials and a Pooled International Cohort
Ann Neurol 92:364-378, Sarraj, A.,et al, 2022
Does Capturing Debris During TAVR Prevent Strokes?
NEJM 387:1318-1319, Carroll, J.D. & Saver, J.L., 2022
Investigating Outcomes Post-Endovascular Thrombectomy in Acute Stroke Patients with Cancer
Neurol 99:e2583-e2592, Shapiro,S.D.,et al, 2022
Administering Thrombolysis for Acute Ischemic Stroke in Patients Taking Direct Oral Anticoagulants
JAMA Neurol 78:515-518, Seiffge, D.J.,et al, 2021
Endovascular Therapy for Stroke Due to Basilar-Artery Occlusion
NEJM 384:1910-1920,1954, Langezaal, L.C.M.,et al, 2021
Medical Management vs Mechanical Thrombectomy for Mild Strokes
JAMA Neurol 77:16-24, Goyal, N.,et al, 2020
Thrombolytic Therapy for Acute Central Retinal Artery Occlusion
Stroke 51:687-695, Mac Grory, B.,et al, 2020
Stridor in Multiple System Atrophy
Neurol 93:630-639, Cortelli, P.,et al, 2019
Intravenous Thrombolysis for Suspected Ischemic Stroke with Seizure at Onset
Ann Neurol 86:770-779, Polymeris, A.A.,et al, 2019